AustralieFrV1, Main, Exploration, bibRecord, 002C49

Inflammatory markers and risk of epithelial ovarian cancer by tumor subtypes: the EPIC cohort

Identifieur interne : 002C49 ( Main/Exploration ); précédent : 002C48; suivant : 002C50

Inflammatory markers and risk of epithelial ovarian cancer by tumor subtypes: the EPIC cohort

Auteurs : Jennifer Ose [Allemagne] ; Helena Schock [Allemagne] ; Anne Tjonneland [Danemark] ; Louise Hansen [Danemark] ; Kim Overvad [Danemark] ; Laure Dossus [France] ; Francoise Clavel-Chapelon [France] ; Laura Baglietto [Australie] ; Heiner Boeing [Allemagne] ; Antonia Trichopolou [Grèce] ; Vassiliki Benetou [Grèce] ; Pagona Lagiou [Grèce, États-Unis] ; Giovanna Masala ; Giovanna Tagliabue [Italie] ; Rosario Tumino [Italie] ; Carlotta Sacerdote [Italie] ; Amalia Mattiello [Italie] ; H. Bas Bueno De Mesquita [Pays-Bas, Royaume-Uni, Malaisie] ; Petra H M. Peeters ; N Charlotte Onland-Moret [Pays-Bas] ; Elisabete Weiderpass [Norvège, Suède, Finlande] ; Inger T. Gram [Norvège] ; Soledad Sánchez [Espagne] ; Mireia Obon-Santacana [Espagne] ; Maria-José Sànchez-Pérez [Espagne] ; Nerea Larra Aga [Espagne] ; José María Huerta Casta O [Espagne] ; Eva Ardanaz [Espagne] ; Jenny Br Ndstedt [Suède] ; Eva Lundin [Suède] ; Annika Idahl [Suède] ; Ruth C. Travis [Royaume-Uni] ; Kay-Tee Khaw [Royaume-Uni] ; Sabina Rinaldi [France] ; Isabelle Romieu [France] ; Melissa A. Merrit [Royaume-Uni] ; Marc J. Gunter [Royaume-Uni] ; Elio Riboli [Royaume-Uni] ; Rudolf Kaaks [Allemagne] ; Renée T. Fortner [Allemagne]

Source :

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology [ 1055-9965 ] ; 2015.

RBID : PMC:4454588

Descripteurs français

English descriptors

KwdEn :
- Adenocarcinoma, Clear Cell (blood), Adenocarcinoma, Clear Cell (etiology), Adenocarcinoma, Clear Cell (pathology), Adenocarcinoma, Mucinous (blood), Adenocarcinoma, Mucinous (etiology), Adenocarcinoma, Mucinous (pathology), Adult, Aged, Biomarkers, Tumor (blood), Case-Control Studies, Cystadenocarcinoma, Serous (blood), Cystadenocarcinoma, Serous (etiology), Cystadenocarcinoma, Serous (pathology), Endometrial Neoplasms (blood), Endometrial Neoplasms (etiology), Endometrial Neoplasms (pathology), Female, Follow-Up Studies, Humans, Inflammation (blood), Inflammation (complications), Inflammation (pathology), Inflammation Mediators (blood), Middle Aged, Neoplasm Grading, Neoplasm Invasiveness, Neoplasm Staging, Ovarian Neoplasms (blood), Ovarian Neoplasms (etiology), Ovarian Neoplasms (pathology), Prognosis, Prospective Studies.
MESH :
- chemical , blood : Biomarkers, Tumor, Inflammation Mediators.
- blood : Adenocarcinoma, Clear Cell, Adenocarcinoma, Mucinous, Cystadenocarcinoma, Serous, Endometrial Neoplasms, Inflammation, Ovarian Neoplasms.
- complications : Inflammation.
- etiology : Adenocarcinoma, Clear Cell, Adenocarcinoma, Mucinous, Cystadenocarcinoma, Serous, Endometrial Neoplasms, Ovarian Neoplasms.
- pathology : Adenocarcinoma, Clear Cell, Adenocarcinoma, Mucinous, Cystadenocarcinoma, Serous, Endometrial Neoplasms, Inflammation, Ovarian Neoplasms.
- Adult, Aged, Case-Control Studies, Female, Follow-Up Studies, Humans, Middle Aged, Neoplasm Grading, Neoplasm Invasiveness, Neoplasm Staging, Prognosis, Prospective Studies.

Abstract

Background

Evidence suggests an etiologic role for inflammation in ovarian carcinogenesis and heterogeneity between tumor subtypes and anthropometric indices. Prospective studies on circulating inflammatory markers and epithelial invasive ovarian cancer (EOC) have predominantly investigated overall risk; data characterizing risk by tumor characteristics (histology, grade, stage, dualistic model of ovarian carcinogenesis) and anthropometric indices are sparse.

Methods

We conducted a nested case-control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort to evaluate C-reactive protein (CRP), interleukin-6 (IL-6), and EOC risk by tumor characteristics. A total of 754 eligible EOC cases were identified; two controls (n=1,497) were matched per case. We used multivariable conditional logistic regression to assess associations.

Results

CRP and IL-6 were not associated with overall EOC risk. However, consistent with prior research, CRP >10 vs. CRP ≤1 mg/L was associated with higher overall EOC risk (OR=1.67 [1.03 - 2.70]). We did not observe significant associations or heterogeneity in analyses by tumor characteristics. In analyses stratified by waist circumference, inflammatory markers were associated with higher risk among women with higher waist circumference; no association was observed for women with normal waist circumference: (e.g., IL-6: waist ≤80: OR_log2=0.97 [0.81 - 1.16]; waist >88: OR_log2=1.78 [1.28 - 2.48], p_{heterogeneity} ≤0.01).

Conclusions

Our data suggest that high CRP is associated with increased risk of overall EOC, and that IL-6 and CRP may be associated with EOC risk among women with higher adiposity.

Impact

Our data add to global evidence that ovarian carcinogenesis may be promoted by an inflammatory milieu.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454588

DOI: 10.1158/1055-9965.EPI-14-1279-T
PubMed: 25855626
PubMed Central: 4454588

Affiliations:

Allemagne, Australie, Danemark, Espagne, Finlande, France, Grèce, Italie, Malaisie, Norvège, Pays-Bas, Royaume-Uni, Suède, États-Unis
Angleterre, Angleterre de l'Est, Attique (région), Auvergne-Rhône-Alpes, Bade-Wurtemberg, Catalogne, District de Karlsruhe, Grand Londres, Hovedstaden, Massachusetts, Oxfordshire, Piémont, Rhône-Alpes, Svealand, Utrecht (province), Victoria (État), Østlandet
Athènes, Barcelone, Cambridge, Copenhague, Heidelberg, Londres, Lyon, Melbourne, Oslo, Oxford, Stockholm, Turin, Utrecht
Université d'Oxford, Université de Cambridge, Université de Melbourne

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Inflammatory markers and risk of epithelial ovarian cancer by tumor subtypes: the EPIC cohort</title>
<author><name sortKey="Ose, Jennifer" sort="Ose, Jennifer" uniqKey="Ose J" first="Jennifer" last="Ose">Jennifer Ose</name>
<affiliation wicri:level="3"><nlm:aff id="A1">Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schock, Helena" sort="Schock, Helena" uniqKey="Schock H" first="Helena" last="Schock">Helena Schock</name>
<affiliation wicri:level="3"><nlm:aff id="A1">Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tjonneland, Anne" sort="Tjonneland, Anne" uniqKey="Tjonneland A" first="Anne" last="Tjonneland">Anne Tjonneland</name>
<affiliation wicri:level="3"><nlm:aff id="A2">Danish Cancer Society Research Center, Copenhagen, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Danish Cancer Society Research Center, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hansen, Louise" sort="Hansen, Louise" uniqKey="Hansen L" first="Louise" last="Hansen">Louise Hansen</name>
<affiliation wicri:level="3"><nlm:aff id="A2">Danish Cancer Society Research Center, Copenhagen, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Danish Cancer Society Research Center, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name>
<affiliation wicri:level="1"><nlm:aff id="A3">Department of Public Health, Section for Epidemiology Danish Cancer, Aarhus University, Aarhus, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department of Public Health, Section for Epidemiology Danish Cancer, Aarhus University, Aarhus</wicri:regionArea>
<wicri:noRegion>Aarhus</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dossus, Laure" sort="Dossus, Laure" uniqKey="Dossus L" first="Laure" last="Dossus">Laure Dossus</name>
<affiliation wicri:level="1"><nlm:aff id="A4">INSERM, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A5">Univ Paris Sud, UMRS 1018, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Univ Paris Sud, UMRS 1018, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A6">IGR, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>IGR, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name>
<affiliation wicri:level="1"><nlm:aff id="A4">INSERM, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A5">Univ Paris Sud, UMRS 1018, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Univ Paris Sud, UMRS 1018, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A6">IGR, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>IGR, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name>
<affiliation wicri:level="3"><nlm:aff id="A7">Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Australia.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Australie</country>
<wicri:regionArea>Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne</wicri:regionArea>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="A8">Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Australia.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Australie</country>
<wicri:regionArea>Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne</wicri:regionArea>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
<orgName type="university">Université de Melbourne</orgName>
</affiliation>
</author>
<author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name>
<affiliation wicri:level="1"><nlm:aff id="A9">Department of Epidemiology, German Institute of Human Nutrition (DIfE) Potsdam-Rehbrücke, Nuthetal, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Epidemiology, German Institute of Human Nutrition (DIfE) Potsdam-Rehbrücke, Nuthetal</wicri:regionArea>
<wicri:noRegion>Nuthetal</wicri:noRegion>
<wicri:noRegion>Nuthetal</wicri:noRegion>
<wicri:noRegion>Nuthetal</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Trichopolou, Antonia" sort="Trichopolou, Antonia" uniqKey="Trichopolou A" first="Antonia" last="Trichopolou">Antonia Trichopolou</name>
<affiliation wicri:level="1"><nlm:aff id="A10">Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27</wicri:regionArea>
<wicri:noRegion>GR-115 27</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A11">Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens</wicri:regionArea>
<placeName><settlement type="city">Athènes</settlement>
<region nuts="2" type="region">Attique (région)</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A12">Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27</wicri:regionArea>
<wicri:noRegion>GR-115 27</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benetou, Vassiliki" sort="Benetou, Vassiliki" uniqKey="Benetou V" first="Vassiliki" last="Benetou">Vassiliki Benetou</name>
<affiliation wicri:level="1"><nlm:aff id="A10">Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27</wicri:regionArea>
<wicri:noRegion>GR-115 27</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A11">Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens</wicri:regionArea>
<placeName><settlement type="city">Athènes</settlement>
<region nuts="2" type="region">Attique (région)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name>
<affiliation wicri:level="3"><nlm:aff id="A11">Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens</wicri:regionArea>
<placeName><settlement type="city">Athènes</settlement>
<region nuts="2" type="region">Attique (région)</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A12">Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27</wicri:regionArea>
<wicri:noRegion>GR-115 27</wicri:noRegion>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A13">Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name>
<affiliation><nlm:aff id="A14">Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute – ISPO, Florence – Italy</nlm:aff>
<wicri:noCountry code="subfield">Florence – Italy</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tagliabue, Giovanna" sort="Tagliabue, Giovanna" uniqKey="Tagliabue G" first="Giovanna" last="Tagliabue">Giovanna Tagliabue</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Lombardy Cancer Registry Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Lombardy Cancer Registry Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano</wicri:regionArea>
<wicri:noRegion>Milano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name>
<affiliation wicri:level="1"><nlm:aff id="A16">Cancer Registry and Histopathology Unit, “Civic - M.P. Arezzo” Hospita, ASP Ragusa, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cancer Registry and Histopathology Unit, “Civic - M.P. Arezzo” Hospita, ASP Ragusa</wicri:regionArea>
<wicri:noRegion>ASP Ragusa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sacerdote, Carlotta" sort="Sacerdote, Carlotta" uniqKey="Sacerdote C" first="Carlotta" last="Sacerdote">Carlotta Sacerdote</name>
<affiliation wicri:level="3"><nlm:aff id="A17">Center for Cancer Prevention (CPOPiemonte),Turin, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Center for Cancer Prevention (CPOPiemonte),Turin</wicri:regionArea>
<placeName><settlement type="city">Turin</settlement>
<region type="région" nuts="2">Piémont</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A18">Human Genetic Foundation, Torino, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Human Genetic Foundation, Torino</wicri:regionArea>
<placeName><settlement type="city">Turin</settlement>
<region type="région" nuts="2">Piémont</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mattiello, Amalia" sort="Mattiello, Amalia" uniqKey="Mattiello A" first="Amalia" last="Mattiello">Amalia Mattiello</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Clinical and Experimental Medicine, Federico II University, Naples</wicri:regionArea>
<wicri:noRegion>Naples</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Mesquita, H Bas Bueno" sort="De Mesquita, H Bas Bueno" uniqKey="De Mesquita H" first="H. Bas Bueno" last="De Mesquita">H. Bas Bueno De Mesquita</name>
<affiliation wicri:level="1"><nlm:aff id="A20">Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven</wicri:regionArea>
<wicri:noRegion>Bilthoven</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A21">Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht</wicri:regionArea>
<placeName><settlement type="city">Utrecht</settlement>
<region nuts="2" type="province">Utrecht (province)</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A22">Department of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea>Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur</wicri:regionArea>
<wicri:noRegion>Kuala Lumpur</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Peeters, Petra H M" sort="Peeters, Petra H M" uniqKey="Peeters P" first="Petra H M" last="Peeters">Petra H M. Peeters</name>
<affiliation><nlm:aff id="A24">Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht</nlm:aff>
<wicri:noCountry code="subfield">University Medical Center Utrecht</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name>
<affiliation wicri:level="3"><nlm:aff id="A25">Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht</wicri:regionArea>
<placeName><settlement type="city">Utrecht</settlement>
<region nuts="2" type="province">Utrecht (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
<affiliation wicri:level="1"><nlm:aff id="A26">Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Norvège</country>
<wicri:regionArea>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø</wicri:regionArea>
<wicri:noRegion>Tromsø</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A27">Cancer Registry of Norway, Oslo, Norway.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Norvège</country>
<wicri:regionArea>Cancer Registry of Norway, Oslo</wicri:regionArea>
<placeName><settlement type="city">Oslo</settlement>
<region nuts="2">Østlandet</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A28">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A29">Department of Genetic Epidemiology, Folkhälsan Research Center, Helsinki, Finland.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Finlande</country>
<wicri:regionArea>Department of Genetic Epidemiology, Folkhälsan Research Center, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gram, Inger T" sort="Gram, Inger T" uniqKey="Gram I" first="Inger T" last="Gram">Inger T. Gram</name>
<affiliation wicri:level="1"><nlm:aff id="A26">Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Norvège</country>
<wicri:regionArea>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø</wicri:regionArea>
<wicri:noRegion>Tromsø</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sanchez, Soledad" sort="Sanchez, Soledad" uniqKey="Sanchez S" first="Soledad" last="Sánchez">Soledad Sánchez</name>
<affiliation wicri:level="1"><nlm:aff id="A30">Public Health Directorate, Asturias, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Directorate, Asturias</wicri:regionArea>
<wicri:noRegion>Asturias</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Obon Santacana, Mireia" sort="Obon Santacana, Mireia" uniqKey="Obon Santacana M" first="Mireia" last="Obon-Santacana">Mireia Obon-Santacana</name>
<affiliation wicri:level="3"><nlm:aff id="A31">Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sanchez Perez, Maria Jose" sort="Sanchez Perez, Maria Jose" uniqKey="Sanchez Perez M" first="Maria-José" last="Sànchez-Pérez">Maria-José Sànchez-Pérez</name>
<affiliation wicri:level="1"><nlm:aff id="A32">CIBER de Epidemiología y Salud Pública (CIBERESP), Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A33">Andalusian School of Public Health. Instituto de Investigación Biosanitaria ibs.GRANADA. Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Andalusian School of Public Health. Instituto de Investigación Biosanitaria ibs.GRANADA. Hospitales Universitarios de Granada/Universidad de Granada, Granada</wicri:regionArea>
<wicri:noRegion>Granada</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Larra Aga, Nerea" sort="Larra Aga, Nerea" uniqKey="Larra Aga N" first="Nerea" last="Larra Aga">Nerea Larra Aga</name>
<affiliation wicri:level="1"><nlm:aff id="A32">CIBER de Epidemiología y Salud Pública (CIBERESP), Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A34">Public Health Division of Gipuzkoa-BIODONOSTIA, Basque Regional Health Department, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Division of Gipuzkoa-BIODONOSTIA, Basque Regional Health Department</wicri:regionArea>
<wicri:noRegion>Basque Regional Health Department</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Casta O, Jose Maria Huerta" sort="Casta O, Jose Maria Huerta" uniqKey="Casta O J" first="José María Huerta" last="Casta O">José María Huerta Casta O</name>
<affiliation wicri:level="1"><nlm:aff id="A32">CIBER de Epidemiología y Salud Pública (CIBERESP), Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A35">Department of Epidemiology, Murcia Regional Health Authority, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Epidemiology, Murcia Regional Health Authority</wicri:regionArea>
<wicri:noRegion>Murcia Regional Health Authority</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ardanaz, Eva" sort="Ardanaz, Eva" uniqKey="Ardanaz E" first="Eva" last="Ardanaz">Eva Ardanaz</name>
<affiliation wicri:level="1"><nlm:aff id="A32">CIBER de Epidemiología y Salud Pública (CIBERESP), Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A36">Navarre Public Health Institute, Pamplona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Navarre Public Health Institute, Pamplona</wicri:regionArea>
<wicri:noRegion>Pamplona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Br Ndstedt, Jenny" sort="Br Ndstedt, Jenny" uniqKey="Br Ndstedt J" first="Jenny" last="Br Ndstedt">Jenny Br Ndstedt</name>
<affiliation wicri:level="1"><nlm:aff id="A37">Department of Surgery, Skåne University Hospital, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Surgery, Skåne University Hospital, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A38">Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Skåne University Hospital, Lund, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Skåne University Hospital, Lund</wicri:regionArea>
<wicri:noRegion>Lund</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lundin, Eva" sort="Lundin, Eva" uniqKey="Lundin E" first="Eva" last="Lundin">Eva Lundin</name>
<affiliation wicri:level="1"><nlm:aff id="A39">Department of Medical Biosciences, Pathology, Umea° University, Umea°, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Biosciences, Pathology, Umea° University, Umea°</wicri:regionArea>
<wicri:noRegion>Umea°</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Idahl, Annika" sort="Idahl, Annika" uniqKey="Idahl A" first="Annika" last="Idahl">Annika Idahl</name>
<affiliation wicri:level="1"><nlm:aff id="A40">Department of Clinical Sciences, Obstetrics and Gynecology, Umea° University, Umea°, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Obstetrics and Gynecology, Umea° University, Umea°</wicri:regionArea>
<wicri:noRegion>Umea°</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A41">Department of Public Health and Clinical Medicine, Nutritional research, Umea° University, Umea°, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health and Clinical Medicine, Nutritional research, Umea° University, Umea°</wicri:regionArea>
<wicri:noRegion>Umea°</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name>
<affiliation wicri:level="4"><nlm:aff id="A42">Cancer Epidemiology Unit, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cancer Epidemiology Unit, University of Oxford, Oxford</wicri:regionArea>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name>
<affiliation wicri:level="4"><nlm:aff id="A43">Department of Public Health and Primary Care, University of Cambridge, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Public Health and Primary Care, University of Cambridge</wicri:regionArea>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
<orgName type="university">Université de Cambridge</orgName>
</affiliation>
</author>
<author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name>
<affiliation wicri:level="3"><nlm:aff id="A44">Biomarkers Group, International Agency for Research on Cancer, Lyon, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Biomarkers Group, International Agency for Research on Cancer, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Romieu, Isabelle" sort="Romieu, Isabelle" uniqKey="Romieu I" first="Isabelle" last="Romieu">Isabelle Romieu</name>
<affiliation wicri:level="3"><nlm:aff id="A44">Biomarkers Group, International Agency for Research on Cancer, Lyon, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Biomarkers Group, International Agency for Research on Cancer, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Merrit, Melissa A" sort="Merrit, Melissa A" uniqKey="Merrit M" first="Melissa A" last="Merrit">Melissa A. Merrit</name>
<affiliation wicri:level="3"><nlm:aff id="A45">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J" last="Gunter">Marc J. Gunter</name>
<affiliation wicri:level="3"><nlm:aff id="A45">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name>
<affiliation wicri:level="3"><nlm:aff id="A45">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name>
<affiliation wicri:level="3"><nlm:aff id="A1">Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fortner, Renee T" sort="Fortner, Renee T" uniqKey="Fortner R" first="Renée T" last="Fortner">Renée T. Fortner</name>
<affiliation wicri:level="3"><nlm:aff id="A1">Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25855626</idno>
<idno type="pmc">4454588</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454588</idno>
<idno type="RBID">PMC:4454588</idno>
<idno type="doi">10.1158/1055-9965.EPI-14-1279-T</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">002096</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002096</idno>
<idno type="wicri:Area/Pmc/Curation">001F50</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001F50</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000F16</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000F16</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">002D28</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002D28</idno>
<idno type="wicri:Area/PubMed/Curation">002C53</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">002C53</idno>
<idno type="wicri:Area/PubMed/Checkpoint">002C53</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">002C53</idno>
<idno type="wicri:Area/Ncbi/Merge">002429</idno>
<idno type="wicri:Area/Ncbi/Curation">002429</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">002429</idno>
<idno type="wicri:doubleKey">1055-9965:2015:Ose J:inflammatory:markers:and</idno>
<idno type="wicri:Area/Main/Merge">002C49</idno>
<idno type="wicri:Area/Main/Curation">002C49</idno>
<idno type="wicri:Area/Main/Exploration">002C49</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Inflammatory markers and risk of epithelial ovarian cancer by tumor subtypes: the EPIC cohort</title>
<author><name sortKey="Ose, Jennifer" sort="Ose, Jennifer" uniqKey="Ose J" first="Jennifer" last="Ose">Jennifer Ose</name>
<affiliation wicri:level="3"><nlm:aff id="A1">Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Schock, Helena" sort="Schock, Helena" uniqKey="Schock H" first="Helena" last="Schock">Helena Schock</name>
<affiliation wicri:level="3"><nlm:aff id="A1">Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Tjonneland, Anne" sort="Tjonneland, Anne" uniqKey="Tjonneland A" first="Anne" last="Tjonneland">Anne Tjonneland</name>
<affiliation wicri:level="3"><nlm:aff id="A2">Danish Cancer Society Research Center, Copenhagen, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Danish Cancer Society Research Center, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hansen, Louise" sort="Hansen, Louise" uniqKey="Hansen L" first="Louise" last="Hansen">Louise Hansen</name>
<affiliation wicri:level="3"><nlm:aff id="A2">Danish Cancer Society Research Center, Copenhagen, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Danish Cancer Society Research Center, Copenhagen</wicri:regionArea>
<placeName><settlement type="city">Copenhague</settlement>
<region type="région" nuts="2">Hovedstaden</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name>
<affiliation wicri:level="1"><nlm:aff id="A3">Department of Public Health, Section for Epidemiology Danish Cancer, Aarhus University, Aarhus, Denmark</nlm:aff>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Department of Public Health, Section for Epidemiology Danish Cancer, Aarhus University, Aarhus</wicri:regionArea>
<wicri:noRegion>Aarhus</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Dossus, Laure" sort="Dossus, Laure" uniqKey="Dossus L" first="Laure" last="Dossus">Laure Dossus</name>
<affiliation wicri:level="1"><nlm:aff id="A4">INSERM, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A5">Univ Paris Sud, UMRS 1018, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Univ Paris Sud, UMRS 1018, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A6">IGR, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>IGR, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name>
<affiliation wicri:level="1"><nlm:aff id="A4">INSERM, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM, Centre for research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women’s Health team, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A5">Univ Paris Sud, UMRS 1018, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Univ Paris Sud, UMRS 1018, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A6">IGR, F-94805, Villejuif, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>IGR, F-94805, Villejuif</wicri:regionArea>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
<wicri:noRegion>94805, Villejuif</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name>
<affiliation wicri:level="3"><nlm:aff id="A7">Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne, Australia.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Australie</country>
<wicri:regionArea>Cancer Epidemiology Centre, Cancer Council of Victoria, Melbourne</wicri:regionArea>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
</affiliation>
<affiliation wicri:level="4"><nlm:aff id="A8">Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Australia.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Australie</country>
<wicri:regionArea>Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne</wicri:regionArea>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
<orgName type="university">Université de Melbourne</orgName>
</affiliation>
</author>
<author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name>
<affiliation wicri:level="1"><nlm:aff id="A9">Department of Epidemiology, German Institute of Human Nutrition (DIfE) Potsdam-Rehbrücke, Nuthetal, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Department of Epidemiology, German Institute of Human Nutrition (DIfE) Potsdam-Rehbrücke, Nuthetal</wicri:regionArea>
<wicri:noRegion>Nuthetal</wicri:noRegion>
<wicri:noRegion>Nuthetal</wicri:noRegion>
<wicri:noRegion>Nuthetal</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Trichopolou, Antonia" sort="Trichopolou, Antonia" uniqKey="Trichopolou A" first="Antonia" last="Trichopolou">Antonia Trichopolou</name>
<affiliation wicri:level="1"><nlm:aff id="A10">Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27</wicri:regionArea>
<wicri:noRegion>GR-115 27</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A11">Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens</wicri:regionArea>
<placeName><settlement type="city">Athènes</settlement>
<region nuts="2" type="region">Attique (région)</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A12">Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27</wicri:regionArea>
<wicri:noRegion>GR-115 27</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Benetou, Vassiliki" sort="Benetou, Vassiliki" uniqKey="Benetou V" first="Vassiliki" last="Benetou">Vassiliki Benetou</name>
<affiliation wicri:level="1"><nlm:aff id="A10">Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Hellenic Health Foundation, 13 Kaisareias Street, Athens, GR-115 27</wicri:regionArea>
<wicri:noRegion>GR-115 27</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A11">Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens</wicri:regionArea>
<placeName><settlement type="city">Athènes</settlement>
<region nuts="2" type="region">Attique (région)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name>
<affiliation wicri:level="3"><nlm:aff id="A11">Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, 75 M. Asias Street, Goudi, GR-115 27, Athens</wicri:regionArea>
<placeName><settlement type="city">Athènes</settlement>
<region nuts="2" type="region">Attique (région)</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A12">Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27, Greece</nlm:aff>
<country xml:lang="fr">Grèce</country>
<wicri:regionArea>Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens, GR-115 27</wicri:regionArea>
<wicri:noRegion>GR-115 27</wicri:noRegion>
</affiliation>
<affiliation wicri:level="2"><nlm:aff id="A13">Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115</wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name>
<affiliation><nlm:aff id="A14">Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute – ISPO, Florence – Italy</nlm:aff>
<wicri:noCountry code="subfield">Florence – Italy</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tagliabue, Giovanna" sort="Tagliabue, Giovanna" uniqKey="Tagliabue G" first="Giovanna" last="Tagliabue">Giovanna Tagliabue</name>
<affiliation wicri:level="1"><nlm:aff id="A15">Lombardy Cancer Registry Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Lombardy Cancer Registry Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano</wicri:regionArea>
<wicri:noRegion>Milano</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name>
<affiliation wicri:level="1"><nlm:aff id="A16">Cancer Registry and Histopathology Unit, “Civic - M.P. Arezzo” Hospita, ASP Ragusa, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Cancer Registry and Histopathology Unit, “Civic - M.P. Arezzo” Hospita, ASP Ragusa</wicri:regionArea>
<wicri:noRegion>ASP Ragusa</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sacerdote, Carlotta" sort="Sacerdote, Carlotta" uniqKey="Sacerdote C" first="Carlotta" last="Sacerdote">Carlotta Sacerdote</name>
<affiliation wicri:level="3"><nlm:aff id="A17">Center for Cancer Prevention (CPOPiemonte),Turin, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Center for Cancer Prevention (CPOPiemonte),Turin</wicri:regionArea>
<placeName><settlement type="city">Turin</settlement>
<region type="région" nuts="2">Piémont</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A18">Human Genetic Foundation, Torino, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Human Genetic Foundation, Torino</wicri:regionArea>
<placeName><settlement type="city">Turin</settlement>
<region type="région" nuts="2">Piémont</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mattiello, Amalia" sort="Mattiello, Amalia" uniqKey="Mattiello A" first="Amalia" last="Mattiello">Amalia Mattiello</name>
<affiliation wicri:level="1"><nlm:aff id="A19">Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy</nlm:aff>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Department of Clinical and Experimental Medicine, Federico II University, Naples</wicri:regionArea>
<wicri:noRegion>Naples</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Mesquita, H Bas Bueno" sort="De Mesquita, H Bas Bueno" uniqKey="De Mesquita H" first="H. Bas Bueno" last="De Mesquita">H. Bas Bueno De Mesquita</name>
<affiliation wicri:level="1"><nlm:aff id="A20">Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department for Determinants of Chronic Diseases (DCD), National Institute for Public Health and the Environment (RIVM), Bilthoven</wicri:regionArea>
<wicri:noRegion>Bilthoven</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A21">Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht</wicri:regionArea>
<placeName><settlement type="city">Utrecht</settlement>
<region nuts="2" type="province">Utrecht (province)</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A22">Department of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A23">Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia</nlm:aff>
<country xml:lang="fr">Malaisie</country>
<wicri:regionArea>Department of Social & Preventive Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur</wicri:regionArea>
<wicri:noRegion>Kuala Lumpur</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Peeters, Petra H M" sort="Peeters, Petra H M" uniqKey="Peeters P" first="Petra H M" last="Peeters">Petra H M. Peeters</name>
<affiliation><nlm:aff id="A24">Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht</nlm:aff>
<wicri:noCountry code="subfield">University Medical Center Utrecht</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name>
<affiliation wicri:level="3"><nlm:aff id="A25">Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff>
<country xml:lang="fr">Pays-Bas</country>
<wicri:regionArea>Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht</wicri:regionArea>
<placeName><settlement type="city">Utrecht</settlement>
<region nuts="2" type="province">Utrecht (province)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
<affiliation wicri:level="1"><nlm:aff id="A26">Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Norvège</country>
<wicri:regionArea>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø</wicri:regionArea>
<wicri:noRegion>Tromsø</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A27">Cancer Registry of Norway, Oslo, Norway.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Norvège</country>
<wicri:regionArea>Cancer Registry of Norway, Oslo</wicri:regionArea>
<placeName><settlement type="city">Oslo</settlement>
<region nuts="2">Østlandet</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="A28">Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Suède</country>
<wicri:regionArea>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm</wicri:regionArea>
<placeName><settlement type="city">Stockholm</settlement>
<region nuts="2">Svealand</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A29">Department of Genetic Epidemiology, Folkhälsan Research Center, Helsinki, Finland.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Finlande</country>
<wicri:regionArea>Department of Genetic Epidemiology, Folkhälsan Research Center, Helsinki</wicri:regionArea>
<wicri:noRegion>Helsinki</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gram, Inger T" sort="Gram, Inger T" uniqKey="Gram I" first="Inger T" last="Gram">Inger T. Gram</name>
<affiliation wicri:level="1"><nlm:aff id="A26">Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø, Norway.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">Norvège</country>
<wicri:regionArea>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, Tromsø</wicri:regionArea>
<wicri:noRegion>Tromsø</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sanchez, Soledad" sort="Sanchez, Soledad" uniqKey="Sanchez S" first="Soledad" last="Sánchez">Soledad Sánchez</name>
<affiliation wicri:level="1"><nlm:aff id="A30">Public Health Directorate, Asturias, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Directorate, Asturias</wicri:regionArea>
<wicri:noRegion>Asturias</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Obon Santacana, Mireia" sort="Obon Santacana, Mireia" uniqKey="Obon Santacana M" first="Mireia" last="Obon-Santacana">Mireia Obon-Santacana</name>
<affiliation wicri:level="3"><nlm:aff id="A31">Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona</wicri:regionArea>
<placeName><settlement type="city">Barcelone</settlement>
<region nuts="2" type="region">Catalogne</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sanchez Perez, Maria Jose" sort="Sanchez Perez, Maria Jose" uniqKey="Sanchez Perez M" first="Maria-José" last="Sànchez-Pérez">Maria-José Sànchez-Pérez</name>
<affiliation wicri:level="1"><nlm:aff id="A32">CIBER de Epidemiología y Salud Pública (CIBERESP), Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A33">Andalusian School of Public Health. Instituto de Investigación Biosanitaria ibs.GRANADA. Hospitales Universitarios de Granada/Universidad de Granada, Granada, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Andalusian School of Public Health. Instituto de Investigación Biosanitaria ibs.GRANADA. Hospitales Universitarios de Granada/Universidad de Granada, Granada</wicri:regionArea>
<wicri:noRegion>Granada</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Larra Aga, Nerea" sort="Larra Aga, Nerea" uniqKey="Larra Aga N" first="Nerea" last="Larra Aga">Nerea Larra Aga</name>
<affiliation wicri:level="1"><nlm:aff id="A32">CIBER de Epidemiología y Salud Pública (CIBERESP), Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A34">Public Health Division of Gipuzkoa-BIODONOSTIA, Basque Regional Health Department, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Public Health Division of Gipuzkoa-BIODONOSTIA, Basque Regional Health Department</wicri:regionArea>
<wicri:noRegion>Basque Regional Health Department</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Casta O, Jose Maria Huerta" sort="Casta O, Jose Maria Huerta" uniqKey="Casta O J" first="José María Huerta" last="Casta O">José María Huerta Casta O</name>
<affiliation wicri:level="1"><nlm:aff id="A32">CIBER de Epidemiología y Salud Pública (CIBERESP), Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A35">Department of Epidemiology, Murcia Regional Health Authority, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Department of Epidemiology, Murcia Regional Health Authority</wicri:regionArea>
<wicri:noRegion>Murcia Regional Health Authority</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ardanaz, Eva" sort="Ardanaz, Eva" uniqKey="Ardanaz E" first="Eva" last="Ardanaz">Eva Ardanaz</name>
<affiliation wicri:level="1"><nlm:aff id="A32">CIBER de Epidemiología y Salud Pública (CIBERESP), Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP)</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A36">Navarre Public Health Institute, Pamplona, Spain</nlm:aff>
<country xml:lang="fr">Espagne</country>
<wicri:regionArea>Navarre Public Health Institute, Pamplona</wicri:regionArea>
<wicri:noRegion>Pamplona</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Br Ndstedt, Jenny" sort="Br Ndstedt, Jenny" uniqKey="Br Ndstedt J" first="Jenny" last="Br Ndstedt">Jenny Br Ndstedt</name>
<affiliation wicri:level="1"><nlm:aff id="A37">Department of Surgery, Skåne University Hospital, Malmö, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Surgery, Skåne University Hospital, Malmö</wicri:regionArea>
<wicri:noRegion>Malmö</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A38">Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Skåne University Hospital, Lund, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Division of Oncology and Pathology, Lund University, Skåne University Hospital, Lund</wicri:regionArea>
<wicri:noRegion>Lund</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lundin, Eva" sort="Lundin, Eva" uniqKey="Lundin E" first="Eva" last="Lundin">Eva Lundin</name>
<affiliation wicri:level="1"><nlm:aff id="A39">Department of Medical Biosciences, Pathology, Umea° University, Umea°, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Medical Biosciences, Pathology, Umea° University, Umea°</wicri:regionArea>
<wicri:noRegion>Umea°</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Idahl, Annika" sort="Idahl, Annika" uniqKey="Idahl A" first="Annika" last="Idahl">Annika Idahl</name>
<affiliation wicri:level="1"><nlm:aff id="A40">Department of Clinical Sciences, Obstetrics and Gynecology, Umea° University, Umea°, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Clinical Sciences, Obstetrics and Gynecology, Umea° University, Umea°</wicri:regionArea>
<wicri:noRegion>Umea°</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="A41">Department of Public Health and Clinical Medicine, Nutritional research, Umea° University, Umea°, Sweden</nlm:aff>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Department of Public Health and Clinical Medicine, Nutritional research, Umea° University, Umea°</wicri:regionArea>
<wicri:noRegion>Umea°</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name>
<affiliation wicri:level="4"><nlm:aff id="A42">Cancer Epidemiology Unit, University of Oxford, Oxford, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Cancer Epidemiology Unit, University of Oxford, Oxford</wicri:regionArea>
<placeName><settlement type="city">Oxford</settlement>
<region type="country">Angleterre</region>
<region type="comté" nuts="2">Oxfordshire</region>
<settlement type="city">Oxford</settlement>
</placeName>
<orgName type="university">Université d'Oxford</orgName>
</affiliation>
</author>
<author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name>
<affiliation wicri:level="4"><nlm:aff id="A43">Department of Public Health and Primary Care, University of Cambridge, United Kingdom</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Public Health and Primary Care, University of Cambridge</wicri:regionArea>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
<orgName type="university">Université de Cambridge</orgName>
</affiliation>
</author>
<author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name>
<affiliation wicri:level="3"><nlm:aff id="A44">Biomarkers Group, International Agency for Research on Cancer, Lyon, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Biomarkers Group, International Agency for Research on Cancer, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Romieu, Isabelle" sort="Romieu, Isabelle" uniqKey="Romieu I" first="Isabelle" last="Romieu">Isabelle Romieu</name>
<affiliation wicri:level="3"><nlm:aff id="A44">Biomarkers Group, International Agency for Research on Cancer, Lyon, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Biomarkers Group, International Agency for Research on Cancer, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Merrit, Melissa A" sort="Merrit, Melissa A" uniqKey="Merrit M" first="Melissa A" last="Merrit">Melissa A. Merrit</name>
<affiliation wicri:level="3"><nlm:aff id="A45">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J" last="Gunter">Marc J. Gunter</name>
<affiliation wicri:level="3"><nlm:aff id="A45">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name>
<affiliation wicri:level="3"><nlm:aff id="A45">Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London</wicri:regionArea>
<placeName><settlement type="city">Londres</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Grand Londres</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name>
<affiliation wicri:level="3"><nlm:aff id="A1">Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fortner, Renee T" sort="Fortner, Renee T" uniqKey="Fortner R" first="Renée T" last="Fortner">Renée T. Fortner</name>
<affiliation wicri:level="3"><nlm:aff id="A1">Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany</nlm:aff>
<country xml:lang="fr">Allemagne</country>
<wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg</wicri:regionArea>
<placeName><region type="land" nuts="1">Bade-Wurtemberg</region>
<region type="district" nuts="2">District de Karlsruhe</region>
<settlement type="city">Heidelberg</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology</title>
<idno type="ISSN">1055-9965</idno>
<idno type="eISSN">1538-7755</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adenocarcinoma, Clear Cell (blood)</term>
<term>Adenocarcinoma, Clear Cell (etiology)</term>
<term>Adenocarcinoma, Clear Cell (pathology)</term>
<term>Adenocarcinoma, Mucinous (blood)</term>
<term>Adenocarcinoma, Mucinous (etiology)</term>
<term>Adenocarcinoma, Mucinous (pathology)</term>
<term>Adult</term>
<term>Aged</term>
<term>Biomarkers, Tumor (blood)</term>
<term>Case-Control Studies</term>
<term>Cystadenocarcinoma, Serous (blood)</term>
<term>Cystadenocarcinoma, Serous (etiology)</term>
<term>Cystadenocarcinoma, Serous (pathology)</term>
<term>Endometrial Neoplasms (blood)</term>
<term>Endometrial Neoplasms (etiology)</term>
<term>Endometrial Neoplasms (pathology)</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Inflammation (blood)</term>
<term>Inflammation (complications)</term>
<term>Inflammation (pathology)</term>
<term>Inflammation Mediators (blood)</term>
<term>Middle Aged</term>
<term>Neoplasm Grading</term>
<term>Neoplasm Invasiveness</term>
<term>Neoplasm Staging</term>
<term>Ovarian Neoplasms (blood)</term>
<term>Ovarian Neoplasms (etiology)</term>
<term>Ovarian Neoplasms (pathology)</term>
<term>Prognosis</term>
<term>Prospective Studies</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Adénocarcinome mucineux (anatomopathologie)</term>
<term>Adénocarcinome mucineux (sang)</term>
<term>Adénocarcinome mucineux (étiologie)</term>
<term>Adénocarcinome à cellules claires (anatomopathologie)</term>
<term>Adénocarcinome à cellules claires (sang)</term>
<term>Adénocarcinome à cellules claires (étiologie)</term>
<term>Cystadénocarcinome séreux (anatomopathologie)</term>
<term>Cystadénocarcinome séreux (sang)</term>
<term>Cystadénocarcinome séreux (étiologie)</term>
<term>Femelle</term>
<term>Grading des tumeurs</term>
<term>Humains</term>
<term>Inflammation ()</term>
<term>Inflammation (anatomopathologie)</term>
<term>Inflammation (sang)</term>
<term>Invasion tumorale</term>
<term>Marqueurs biologiques tumoraux (sang)</term>
<term>Médiateurs de l'inflammation (sang)</term>
<term>Pronostic</term>
<term>Stade de la tumeur</term>
<term>Sujet âgé</term>
<term>Tumeurs de l'endomètre (anatomopathologie)</term>
<term>Tumeurs de l'endomètre (sang)</term>
<term>Tumeurs de l'endomètre (étiologie)</term>
<term>Tumeurs de l'ovaire (anatomopathologie)</term>
<term>Tumeurs de l'ovaire (sang)</term>
<term>Tumeurs de l'ovaire (étiologie)</term>
<term>Études cas-témoins</term>
<term>Études de suivi</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Biomarkers, Tumor</term>
<term>Inflammation Mediators</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Adénocarcinome mucineux</term>
<term>Adénocarcinome à cellules claires</term>
<term>Cystadénocarcinome séreux</term>
<term>Inflammation</term>
<term>Tumeurs de l'endomètre</term>
<term>Tumeurs de l'ovaire</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Adenocarcinoma, Clear Cell</term>
<term>Adenocarcinoma, Mucinous</term>
<term>Cystadenocarcinoma, Serous</term>
<term>Endometrial Neoplasms</term>
<term>Inflammation</term>
<term>Ovarian Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Inflammation</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Adenocarcinoma, Clear Cell</term>
<term>Adenocarcinoma, Mucinous</term>
<term>Cystadenocarcinoma, Serous</term>
<term>Endometrial Neoplasms</term>
<term>Ovarian Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Adenocarcinoma, Clear Cell</term>
<term>Adenocarcinoma, Mucinous</term>
<term>Cystadenocarcinoma, Serous</term>
<term>Endometrial Neoplasms</term>
<term>Inflammation</term>
<term>Ovarian Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Adénocarcinome mucineux</term>
<term>Adénocarcinome à cellules claires</term>
<term>Cystadénocarcinome séreux</term>
<term>Inflammation</term>
<term>Marqueurs biologiques tumoraux</term>
<term>Médiateurs de l'inflammation</term>
<term>Tumeurs de l'endomètre</term>
<term>Tumeurs de l'ovaire</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Adénocarcinome mucineux</term>
<term>Adénocarcinome à cellules claires</term>
<term>Cystadénocarcinome séreux</term>
<term>Tumeurs de l'endomètre</term>
<term>Tumeurs de l'ovaire</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Case-Control Studies</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Middle Aged</term>
<term>Neoplasm Grading</term>
<term>Neoplasm Invasiveness</term>
<term>Neoplasm Staging</term>
<term>Prognosis</term>
<term>Prospective Studies</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Grading des tumeurs</term>
<term>Humains</term>
<term>Inflammation</term>
<term>Invasion tumorale</term>
<term>Pronostic</term>
<term>Stade de la tumeur</term>
<term>Sujet âgé</term>
<term>Études cas-témoins</term>
<term>Études de suivi</term>
<term>Études prospectives</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title>
<p id="P1">Evidence suggests an etiologic role for inflammation in ovarian carcinogenesis and heterogeneity between tumor subtypes and anthropometric indices. Prospective studies on circulating inflammatory markers and epithelial invasive ovarian cancer (EOC) have predominantly investigated overall risk; data characterizing risk by tumor characteristics (histology, grade, stage, dualistic model of ovarian carcinogenesis) and anthropometric indices are sparse.</p>
</sec>
<sec id="S2"><title>Methods</title>
<p id="P2">We conducted a nested case-control study in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort to evaluate C-reactive protein (CRP), interleukin-6 (IL-6), and EOC risk by tumor characteristics. A total of 754 eligible EOC cases were identified; two controls (n=1,497) were matched per case. We used multivariable conditional logistic regression to assess associations.</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">CRP and IL-6 were not associated with overall EOC risk. However, consistent with prior research, CRP >10 vs. CRP ≤1 mg/L was associated with higher overall EOC risk (OR=1.67 [1.03 - 2.70]). We did not observe significant associations or heterogeneity in analyses by tumor characteristics. In analyses stratified by waist circumference, inflammatory markers were associated with higher risk among women with higher waist circumference; no association was observed for women with normal waist circumference: (e.g., IL-6: waist ≤80: OR<sub>log2</sub>
=0.97 [0.81 - 1.16]; waist >88: OR<sub>log2</sub>
=1.78 [1.28 - 2.48], p<sub>heterogeneity</sub>
 ≤0.01).</p>
</sec>
<sec id="S4"><title>Conclusions</title>
<p id="P4">Our data suggest that high CRP is associated with increased risk of overall EOC, and that IL-6 and CRP may be associated with EOC risk among women with higher adiposity.</p>
</sec>
<sec id="S5"><title>Impact</title>
<p id="P5">Our data add to global evidence that ovarian carcinogenesis may be promoted by an inflammatory milieu.</p>
</sec>
</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Australie</li>
<li>Danemark</li>
<li>Espagne</li>
<li>Finlande</li>
<li>France</li>
<li>Grèce</li>
<li>Italie</li>
<li>Malaisie</li>
<li>Norvège</li>
<li>Pays-Bas</li>
<li>Royaume-Uni</li>
<li>Suède</li>
<li>États-Unis</li>
</country>
<region><li>Angleterre</li>
<li>Angleterre de l'Est</li>
<li>Attique (région)</li>
<li>Auvergne-Rhône-Alpes</li>
<li>Bade-Wurtemberg</li>
<li>Catalogne</li>
<li>District de Karlsruhe</li>
<li>Grand Londres</li>
<li>Hovedstaden</li>
<li>Massachusetts</li>
<li>Oxfordshire</li>
<li>Piémont</li>
<li>Rhône-Alpes</li>
<li>Svealand</li>
<li>Utrecht (province)</li>
<li>Victoria (État)</li>
<li>Østlandet</li>
</region>
<settlement><li>Athènes</li>
<li>Barcelone</li>
<li>Cambridge</li>
<li>Copenhague</li>
<li>Heidelberg</li>
<li>Londres</li>
<li>Lyon</li>
<li>Melbourne</li>
<li>Oslo</li>
<li>Oxford</li>
<li>Stockholm</li>
<li>Turin</li>
<li>Utrecht</li>
</settlement>
<orgName><li>Université d'Oxford</li>
<li>Université de Cambridge</li>
<li>Université de Melbourne</li>
</orgName>
</list>
<tree><noCountry><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name>
<name sortKey="Peeters, Petra H M" sort="Peeters, Petra H M" uniqKey="Peeters P" first="Petra H M" last="Peeters">Petra H M. Peeters</name>
</noCountry>
<country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Ose, Jennifer" sort="Ose, Jennifer" uniqKey="Ose J" first="Jennifer" last="Ose">Jennifer Ose</name>
</region>
<name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name>
<name sortKey="Fortner, Renee T" sort="Fortner, Renee T" uniqKey="Fortner R" first="Renée T" last="Fortner">Renée T. Fortner</name>
<name sortKey="Kaaks, Rudolf" sort="Kaaks, Rudolf" uniqKey="Kaaks R" first="Rudolf" last="Kaaks">Rudolf Kaaks</name>
<name sortKey="Schock, Helena" sort="Schock, Helena" uniqKey="Schock H" first="Helena" last="Schock">Helena Schock</name>
</country>
<country name="Danemark"><region name="Hovedstaden"><name sortKey="Tjonneland, Anne" sort="Tjonneland, Anne" uniqKey="Tjonneland A" first="Anne" last="Tjonneland">Anne Tjonneland</name>
</region>
<name sortKey="Hansen, Louise" sort="Hansen, Louise" uniqKey="Hansen L" first="Louise" last="Hansen">Louise Hansen</name>
<name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name>
</country>
<country name="France"><noRegion><name sortKey="Dossus, Laure" sort="Dossus, Laure" uniqKey="Dossus L" first="Laure" last="Dossus">Laure Dossus</name>
</noRegion>
<name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name>
<name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name>
<name sortKey="Clavel Chapelon, Francoise" sort="Clavel Chapelon, Francoise" uniqKey="Clavel Chapelon F" first="Francoise" last="Clavel-Chapelon">Francoise Clavel-Chapelon</name>
<name sortKey="Dossus, Laure" sort="Dossus, Laure" uniqKey="Dossus L" first="Laure" last="Dossus">Laure Dossus</name>
<name sortKey="Dossus, Laure" sort="Dossus, Laure" uniqKey="Dossus L" first="Laure" last="Dossus">Laure Dossus</name>
<name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name>
<name sortKey="Romieu, Isabelle" sort="Romieu, Isabelle" uniqKey="Romieu I" first="Isabelle" last="Romieu">Isabelle Romieu</name>
</country>
<country name="Australie"><region name="Victoria (État)"><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name>
</region>
<name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name>
</country>
<country name="Grèce"><noRegion><name sortKey="Trichopolou, Antonia" sort="Trichopolou, Antonia" uniqKey="Trichopolou A" first="Antonia" last="Trichopolou">Antonia Trichopolou</name>
</noRegion>
<name sortKey="Benetou, Vassiliki" sort="Benetou, Vassiliki" uniqKey="Benetou V" first="Vassiliki" last="Benetou">Vassiliki Benetou</name>
<name sortKey="Benetou, Vassiliki" sort="Benetou, Vassiliki" uniqKey="Benetou V" first="Vassiliki" last="Benetou">Vassiliki Benetou</name>
<name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name>
<name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name>
<name sortKey="Trichopolou, Antonia" sort="Trichopolou, Antonia" uniqKey="Trichopolou A" first="Antonia" last="Trichopolou">Antonia Trichopolou</name>
<name sortKey="Trichopolou, Antonia" sort="Trichopolou, Antonia" uniqKey="Trichopolou A" first="Antonia" last="Trichopolou">Antonia Trichopolou</name>
</country>
<country name="États-Unis"><region name="Massachusetts"><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name>
</region>
</country>
<country name="Italie"><noRegion><name sortKey="Tagliabue, Giovanna" sort="Tagliabue, Giovanna" uniqKey="Tagliabue G" first="Giovanna" last="Tagliabue">Giovanna Tagliabue</name>
</noRegion>
<name sortKey="Mattiello, Amalia" sort="Mattiello, Amalia" uniqKey="Mattiello A" first="Amalia" last="Mattiello">Amalia Mattiello</name>
<name sortKey="Sacerdote, Carlotta" sort="Sacerdote, Carlotta" uniqKey="Sacerdote C" first="Carlotta" last="Sacerdote">Carlotta Sacerdote</name>
<name sortKey="Sacerdote, Carlotta" sort="Sacerdote, Carlotta" uniqKey="Sacerdote C" first="Carlotta" last="Sacerdote">Carlotta Sacerdote</name>
<name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name>
</country>
<country name="Pays-Bas"><noRegion><name sortKey="De Mesquita, H Bas Bueno" sort="De Mesquita, H Bas Bueno" uniqKey="De Mesquita H" first="H. Bas Bueno" last="De Mesquita">H. Bas Bueno De Mesquita</name>
</noRegion>
<name sortKey="De Mesquita, H Bas Bueno" sort="De Mesquita, H Bas Bueno" uniqKey="De Mesquita H" first="H. Bas Bueno" last="De Mesquita">H. Bas Bueno De Mesquita</name>
<name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="De Mesquita, H Bas Bueno" sort="De Mesquita, H Bas Bueno" uniqKey="De Mesquita H" first="H. Bas Bueno" last="De Mesquita">H. Bas Bueno De Mesquita</name>
</region>
<name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J" last="Gunter">Marc J. Gunter</name>
<name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name>
<name sortKey="Merrit, Melissa A" sort="Merrit, Melissa A" uniqKey="Merrit M" first="Melissa A" last="Merrit">Melissa A. Merrit</name>
<name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name>
<name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name>
</country>
<country name="Malaisie"><noRegion><name sortKey="De Mesquita, H Bas Bueno" sort="De Mesquita, H Bas Bueno" uniqKey="De Mesquita H" first="H. Bas Bueno" last="De Mesquita">H. Bas Bueno De Mesquita</name>
</noRegion>
</country>
<country name="Norvège"><noRegion><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
</noRegion>
<name sortKey="Gram, Inger T" sort="Gram, Inger T" uniqKey="Gram I" first="Inger T" last="Gram">Inger T. Gram</name>
<name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
</country>
<country name="Suède"><region name="Svealand"><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
</region>
<name sortKey="Br Ndstedt, Jenny" sort="Br Ndstedt, Jenny" uniqKey="Br Ndstedt J" first="Jenny" last="Br Ndstedt">Jenny Br Ndstedt</name>
<name sortKey="Br Ndstedt, Jenny" sort="Br Ndstedt, Jenny" uniqKey="Br Ndstedt J" first="Jenny" last="Br Ndstedt">Jenny Br Ndstedt</name>
<name sortKey="Idahl, Annika" sort="Idahl, Annika" uniqKey="Idahl A" first="Annika" last="Idahl">Annika Idahl</name>
<name sortKey="Idahl, Annika" sort="Idahl, Annika" uniqKey="Idahl A" first="Annika" last="Idahl">Annika Idahl</name>
<name sortKey="Lundin, Eva" sort="Lundin, Eva" uniqKey="Lundin E" first="Eva" last="Lundin">Eva Lundin</name>
</country>
<country name="Finlande"><noRegion><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name>
</noRegion>
</country>
<country name="Espagne"><noRegion><name sortKey="Sanchez, Soledad" sort="Sanchez, Soledad" uniqKey="Sanchez S" first="Soledad" last="Sánchez">Soledad Sánchez</name>
</noRegion>
<name sortKey="Ardanaz, Eva" sort="Ardanaz, Eva" uniqKey="Ardanaz E" first="Eva" last="Ardanaz">Eva Ardanaz</name>
<name sortKey="Ardanaz, Eva" sort="Ardanaz, Eva" uniqKey="Ardanaz E" first="Eva" last="Ardanaz">Eva Ardanaz</name>
<name sortKey="Casta O, Jose Maria Huerta" sort="Casta O, Jose Maria Huerta" uniqKey="Casta O J" first="José María Huerta" last="Casta O">José María Huerta Casta O</name>
<name sortKey="Casta O, Jose Maria Huerta" sort="Casta O, Jose Maria Huerta" uniqKey="Casta O J" first="José María Huerta" last="Casta O">José María Huerta Casta O</name>
<name sortKey="Larra Aga, Nerea" sort="Larra Aga, Nerea" uniqKey="Larra Aga N" first="Nerea" last="Larra Aga">Nerea Larra Aga</name>
<name sortKey="Larra Aga, Nerea" sort="Larra Aga, Nerea" uniqKey="Larra Aga N" first="Nerea" last="Larra Aga">Nerea Larra Aga</name>
<name sortKey="Obon Santacana, Mireia" sort="Obon Santacana, Mireia" uniqKey="Obon Santacana M" first="Mireia" last="Obon-Santacana">Mireia Obon-Santacana</name>
<name sortKey="Sanchez Perez, Maria Jose" sort="Sanchez Perez, Maria Jose" uniqKey="Sanchez Perez M" first="Maria-José" last="Sànchez-Pérez">Maria-José Sànchez-Pérez</name>
<name sortKey="Sanchez Perez, Maria Jose" sort="Sanchez Perez, Maria Jose" uniqKey="Sanchez Perez M" first="Maria-José" last="Sànchez-Pérez">Maria-José Sànchez-Pérez</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002C49 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002C49 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:4454588
   |texte=   Inflammatory markers and risk of epithelial ovarian cancer by tumor subtypes: the EPIC cohort
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:25855626" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a AustralieFrV1

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

Serveur d'exploration sur les relations entre la France et l'Australie

Inflammatory markers and risk of epithelial ovarian cancer by tumor subtypes: the EPIC cohort

Inflammatory markers and risk of epithelial ovarian cancer by tumor subtypes: the EPIC cohort

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration sur les relations entre la France et l'Australie
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.